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"main disadvantages" is a correct and usable phrase in written English.
For example, you could use it in a sentence like this: "The main disadvantages of the new technology are its high cost and energy requirement."
Exact(60)
Dried fruits also hold one of the main disadvantages of juices: volume.
Their main disadvantages are that they require large sample sizes and long follow-up times.
"One of the main disadvantages is that you have to match your foot color exactly to the pantyhose," she said.
The main disadvantages to hydronic heating systems are they cannot be adapted to accommodate other climate control systems, and the installation costs can be high.
However, radiography has two main disadvantages.
There are two main disadvantages to direct visualization.
The main disadvantages of FFP include the following aspects.
The main disadvantages of TSP include the following aspects.
The main disadvantages of CCP include the following aspects.
The main disadvantages are corrosion and catalyst losses.
On the flipside, survey takers also identified two main disadvantages of working in this industry.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com