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Besides this fluid solid interface condition, a one-voxel-wide plane of solid is added on the faces of the image that are not perpendicular to the main diffusion direction.
In each white voxel of the brain mask white matter fibers were tracked, initiated by 8 seeds, going from voxel to voxel following the main diffusion direction in each traversed voxel.
Before a given tracking iteration, the PDF associated to the local main diffusion direction e1 in each voxel was sampled, resulting in a unique distribution of diffusion directions within the whole brain.
The evaluation of accuracy is a major challenge of tractography and, to the best of the visual assessment of the authors, the reconstructed tracts complemented well both the surrounding anatomy and the displayed DTI information (notably each voxel main diffusion direction).
2) The diffusion profile of each voxel was fitted a tensor using a robust tensor fitting method (Chang et al. 2005), and 3) the principal eigenvector of the eigenvalue decomposition of the fitted tensor was taken as the main diffusion direction within each voxel.
To this end, within each voxel eight seeds were started, and the main diffusion direction was followed from voxel to voxel, until one of the stopping criteria was met, being when the streamline reached a voxel with a low FA value (<0.1), when a streamline left the brain mask or when a reconstructed streamline made a sharp turn (>60°).
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Similarly, the number and orientation of the main diffusion directions are preserved, but, what is crucial, the information about diffusion coherence is lost.
Several exclusion ROIs eliminating tracts intersecting them were defined solely according to the main diffusion directions to exclude neighbouring tracts to ML.
After these processes, using DTIFit within the FMRIB's diffusion toolbox, the images were calculated to get the FA, λ1 (longitudinal diffusivity) (the magnitude of diffusion along the principal diffusion direction) and λ23 (radial diffusivity) (the magnitude of diffusion in the two orthogonal directions perpendicular to the principal diffusion direction) maps.
The principal diffusion directions of both tensors are displayed.
The axial diffusion direction is thought to reflect the packing density and diameter of axons (Song et al, 2003).
More suggestions(15)
main stream direction
main wind direction
main injection direction
main motion direction
main transport direction
main piping direction
main diffusion barrier
main diffusion path
main commuting direction
main interaction direction
main lobe direction
main diffusion parameter diffusion
main flow direction
main diffusion tensor
main research direction
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