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Besides size, the main difference between a brown dwarf and a planet is their formation.
What is the main difference between a desktop experience and a mobile experience?
The main difference between a traditional two-year contract and T-Mobile's two-year device payment is what happens after that period of time.
Besides being smaller, the main difference between a bacterium and a virus is that the latter can grow and multiply only inside living cells while the bacterium flourishes on non-living material The virus attacks all living matter.
The main difference between a super PAC and a social-welfare group, practically speaking, is that a super PAC has to disclose the identity of its donors, while social-welfare groups generally do not.
The main difference between a hedge fund and the Fed is that the Fed effectively creates its own money, so it doesn't have any borrowing costs, meaning yet more profits.
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The main difference between A-ENS and existing non-dominated sorting methods lies in the fact that A-ENS can only obtain an approximate non-dominated sorting result, whereas the other methods all aim to obtain an accurate result.
The main difference between A-ENS and existing non-dominated sorting algorithms lies in the fact that, instead of identifying the accurate non-dominated sorting result for a given population in existing non-dominated sorting algorithms, A-ENS determines an approximate sorting result by performing at most three-objective comparisons for each pair of solutions.
It can be the main difference between an obscure directory on an official website and a useful map.
The main difference between an interglacial and a glacial period is the opposite representation of woodlands vs. moist environments: the last ones being more represented during cold periods than during warm periods.
At this level, the main difference between an entrepreneurship ecosystem and a digital entrepreneurship ecosystem is that a DEE is populated by digital species while an entrepreneurship ecosystem is populated by entrepreneurial species.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com