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55 Though our main cost effectiveness measure was cost per life year saved not per DALY averted we chose a threshold of one times per capita gross domestic product.
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10 This report provides the main cost-effectiveness and mortality outcomes up to 6 years after randomisation.
The main cost-effectiveness outcome is the incremental cost-effectiveness of each intervention combination, that is, the difference in the percentage of eligible women with mammograms divided by the difference in total cost for each intervention pair.
Table 6 illustrates the main cost-effectiveness results for delivery of the intervention with the cost data relating to the same scenario as considered in table 5 and estimated in the same manner.
We have previously documented a small expected increase in non-16,18 non-16,18Goldie et al, 2003, 2007), although we again found that the impacancershe main cost-effectiveness results was small.
Although in the main cost-effectiveness analyses we accounted for the variability across centres by use of multilevel models for effectiveness and cost estimates, it is possible that the overall results might have been driven by one or two centres with extreme results.
Therefore, the main cost-effectiveness analysis will involve calculating two incremental cost-effectiveness ratios (ICERs) expressing 1) the cost per Quality Adjusted Life Year (QALY, mother unit of analysis) and 2) the cost per live born infant (child unit of analysis).
Because of this limitation, we presented our main cost-effectiveness findings for each technology as a cost-effectiveness ratio compared to no intervention, since the relative test performance of visual inspection and HPV testing methodologies may vary over time in this setting in as-yet-unpredictable ways.
For the main cost-effectiveness evaluation of 3-yearly screening in Australia, and based on the data from the UK and NZ shown in Figure 2, we assumed that if the current reminder-based system was retained, there would be approximately 44% early re-screening before 33 months, whereas if a call-and-recall system was implemented, there would be 11% early rescreening before 33 months.
However, although significant improvements in tool performance have been made since the early days, diamond tools are still the main factor for cost effectiveness.
Main outcome measures Cost effectiveness ratios, incremental cost effectiveness ratios, and screening options' outcomes.
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