Although some variation in the calculated signal intensities was observed, the main results of the computational analysis remained unaffected.
HK carried out the main part of the computational analysis and drafted the manuscript.
The main conclusion of the present computational analysis is that the interaction of plasma and combustion supports a two-way coupling rooted in the electron and neutral energy equations.
The main issue in this work is computational analysis of material parameters variability, deterministic sensitivity as well as of the basic probabilistic characteristics of the homogenized elasticity tensor for Carbon Fiber Reinforced Polymers (CFRP).
The analysis included three main computational steps: (1) calculate a profile for each domain comprised of numbers of the domain in the tested genomes (Supplementary Table 6S), (2) calculate Pearson correlations for each pair of the domain profiles, and (3) find disconnected networks by clustering the correlated profiles according to their pair-wise correlations using a threshold.
The main computational challenges are: (i) flexible image-analysis methods that provide confidence estimates along with the results, that work in more than just one particular case, and that provide a principled way of including prior knowledge about the imaged system and the imaging system.
PR SJJ and DLR developed the main ideas and methodology; PR did the computational analysis and RT-PCR experiments; SJJ and DLR provided feedback and coordination of the project.
In the literature of computational analysis of miRNAs, the two main focuses have long been on identifying miRNA-encoding regions from genomes [ 33– 36] and on predicting the targets of individual miRNAs [ 37, 38].
The main computational tool we used to perform the cost-effectiveness analysis was TreeAge Pro Suite 2009 Release 1.0.2 (TreeAge Software, Inc., Williamstown, MA, US).
We have presented here a global vision of the issues associated with the computational analysis of personalized cancer data, describing the main limitations and possible developments of current approaches and the currently available computational systems.
