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The interim analyses are performed only for the main comparison of ACDF versus ACDP.
The number of subjects to include is estimated on the basis of a main comparison of two groups, an early intervention group and a later intervention group.
The main comparison of the primary end point between the study arms was performed using logistic regression using all randomised patients.
We have made the main comparison of sensitivity and specificity between clinical examination coupled with conventional breast imaging (mammography and breast ultrasound) and CE MRI.
The effect size measured with Cohen's d for the knowledge score main comparison of M5 EBM vs. M5 non-EBM was 0.88 (Table 1).
In the pediatric medication study, the main comparison of interest is 15-month versus baseline, comparing insulin glargine followed by metformin versus metformin alone.
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Figure 7 shows trend lines of three main comparisons of 3D parameters with 2D parameters.
Therefore we have categorised comparisons into (i) main comparisons of interest, and (ii) secondary comparisons of interest (Table 1).
The main comparisons of study conditions with respect to the distribution of time until first instance of smoking will be based on survival analysis methods.
In the adult medication study, the main comparisons of interest will be 15-month measures versus baseline, comparing active medications against placebo.
The main comparisons of microbial diversity within and among horses were made for genus and higher-level classifications as described below.
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