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We found that the subgenus Drosophila is paraphyletic and subdivided into two main clusters: the first containing species traditionally placed in the virilis-repleta radiation and the second assembling species of the immigrans-Hirtodrosophila radiation.
With the PAM the best classification of co-expressed transcripts gave again two main clusters: the testicular transcripts versus the other tissues transcripts.
The hierarchical clustering analysis revealed two main clusters (the ER-positive and ER-negative tumours of the breast), in concordance with results from large-scale microarray analysis.
As well as the two main clusters, the LPS operational population contained four and five individuals, respectively, belonging to the black and yellow clusters.
The genes also partitioned into two main clusters; the larger cluster consisting of genes up-regulated in response to smoking, the smaller cluster containing down-regulated genes.
Unsupervised clustering using pathway deregulation scores of 272 pathways showed that the tumors formed 2 main clusters, the left branch with 12 samples (referred as Cluster 1) and the right with 15 samples.
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The human genome contains two paralogues of the main cluster: the miR-106b/25 and the miR-106a/363 cluster, respectively.
In our application to the genetic profiles of ovarian cancer data, we demonstrated that RidgeRace was able to reconstruct the main clusters of the phenotype distribution.
We employed a nonnegative matrix factorization (NNMF) and model selection approach to extract mutational signatures23,33 from the 96-class profile of the entire cohort (Fig. 4a) identifying 5 main clusters covering the majority of the mutational repertoire (Fig. 4b).
16S rRNA gene sequencing included two strains, S9 and 85, representing two of the three main clusters in the M. ruminalis cluster in Fig. 1.
Hierarchical clustering analysis in the 155 patients resulted in two main clusters, representing the ERα-negative and ERα-positive breast cancer cases.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com