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Hereditary spastic paraplegias (HSPs) are a genetically and clinically heterogeneous group of neurodegenerative disorders whose main clinical feature is progressive spasticity and paresis of the lower limbs (1).
Recurrent excruciating headache ("thunderclap") was the main clinical feature.
Regional Lymphadenopathy (main clinical feature) These areas of lymph node concentration include cervical nodes, axillary nodes, cubital (epitrochlear nodes), and inguinal nodes.
The main clinical feature of TTR-FAP is progressive sensorimotor and autonomic neuropathy.
Incessant and excessive cry was the main clinical feature of colic identified by 430 62.9%) mothers.
Optic atrophy was the main clinical feature of our patient, resembling a severe version of LHON.
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Main clinical features of Type II mixed cryoglobulinemia [1 6].
In Table 3, the main clinical features of each headache type are reported.
Table 1 Main clinical features of the family members Subject gender/age (yrs) Onset, remission, (peak) (yrs) Lifetime occurrence (no.
The main clinical features include subacute onset of cough, fever, dyspnoea and sparse crackles at auscultation [64].
Finally, the different HCRTR1 G1222A genotypes did not seem to modify the main clinical features of the disease.
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