Sentence examples for main chaperone from inspiring English sources

BipA encoding the main chaperone protein in the endoplasmic reticulum (ER) was up-regulated before 24 h and then down-regulated, possibly because that the specific productivity of glucoamylase reached the peak at 24 h and then decreased.

During folding reactions in the matrix, mtHSP70 cooperates closely with the other main chaperone type in the matrix compartment, HSP60 (see section chaperonins).

Together, these observations have led to the hypothesis that SurA is the main chaperone for OMP transport in vivo [93,94], although there is clearly much to learn about the function of this protein at both cellular and molecular levels.

Notably, the gene with the most significantly increased transcript level in B36 was the bipA gene (FDR, 1.1 × 10-7), whish is under transcriptional control of HacA [ 17], and encodes the main chaperone in the ER and is thus important for protein overproduction in A. niger[ 30].

While the main chaperone-related functions typically are associated with the N-, and P-domain of CRTs [1], a recent study showed that the C-terminal part of AtCRT3 is essential for retention of the defective BRI1-9 [29].

This did not explain our findings: the two main chaperones, DnaK and GroEL, were not overproduced in evolved genotypes.

The main guardian chaperone is DnaK because its client proteins spend more time unfolded than clients of GroEL, providing a mechanism for why the cell's capacity to handle stress is more sensitive to DnaK levels.

HSP70, as the main molecular chaperone, plays important roles in protecting against a wide variety of stress stimuli, including heavy metals, inflammation, and oxidative/ischemic injury[6].

Activating transcription factor 6 (ATF6) regulates the main ER chaperone BiP, as well as other components of the protein folding machinery, and induces transcription of itself and of XBP1 (Shoulders et al., 2013), a downstream target of a second UPR sensor, inositol-requiring enzyme-1a (IRERN1 ERN1).

Growth in sputum increased the expression of flagellar structural genes (basal body MS-ring gene fliF; BCAL0525, main flagellin chaperone gene fliS; BCAL0527, C-ring gene fliM; BCAL3506, hook-protein gene flgE; BCAM0987; Table 4) as well as of one regulatory gene (flhD; BCAL0124; Table 4).

Autophagy comprises three main processes – chaperone-mediated autophagy, microautophagy and macroautophagy.