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'main changes are' is a correct and usable phrase in written English
You can use it to introduce a summary of changes that have taken place in a particular situation. For example: "The main changes are that the office hours have been adjusted and the lunch break has been extended."
Exact(26)
Main changes are the control system.
The main changes are designed to encourage the shooting of does instead of bucks.
The main changes are 12 new or updated sections that cover professional practice.
The main changes are in the subtree beneath node 20 (highlighted in gray).
When it comes to customers and product choices, three main changes are likely.
The main changes are the deletion of some profane dialogue and lyrics as well as a song, "Contact," that is sexually explicit.
Similar(34)
One of the main changes is that Linehan has chosen not to theme the programmes.
"In terms of migration, one of the main changes is the increased representation of women who are working abroad to support families at home," Dr. Naufal said.
One of such main changes is related to the emergence of chemical product design (CPD) as a specific and critical new field within the scope of chemical engineering.
The main changes were mainly applied on the use of continuous formative assessment methodologies, to increase feedback, to promote collaborative learning and to engage students in ethical commitment.
Among the main changes is that lenders will be able to use internal assessors, a step banned in the initial code of conduct, but must use various firewalls to ensure their independent views.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com