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While the character of Summer and the world she inhabited seemed to jump off the page, my main challenge during revisions of the script was to make her mother's conversion to Islam believable and tangible.
Since we need to traverse through a section of the GO-Tree that might be fairly large, the main challenge during the development of GFD-Net was the performance of the app.
Patients with a large tumor (>38 cm) were more likely to experience local failure and mucosal necrosis, which became the main challenge during re-irradiation using IMRT, and these patients had a low 5-year OS rate (15.2 %).
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Enzyme recovery and reuse were still the main challenges during the bio-esterification reactions [26, 27].
The modeling and analysis of requirements have been the main challenges during the development of complex systems.
The question of the relationship between humans and their environment has been one of the geographers' main challenges during this century.
One of the main challenges during the freeze-drying process is preserving or rather increasing the re-dispersibility of the NPs upon reconstitution with distilled water or buffered saline.
The main challenge reported during implementation was coordinating shared clinical, technical, and governance procedures across organisations.
The main challenge for the world during 6 K will take the form of a global and multiple risk assessment and management problem.
The main challenge a company faces during transition of the business stage is to have relationship with professionals and convert some of them or take their help in roping in right kind of technical talent for their organization.
The paper reports the main characteristics of the final design as well as the main challenges encountered during the design and testing phase of the key components.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com