Sentence examples for main chain oxygen from inspiring English sources

Moreover, we observed that the imidazole group of MEPLH24 could form a hydrogen bond with the main chain oxygen atom of MEPLG185, which could help improving the structural rigidity of "174-loop" (Fig. 2B).

The R-BSX structural model showed that the main chain oxygen of Met contributes to making two extra hydrogen bonds with the main chain and side chain of Gln2 (Figure 2E).

In addition N13 contacts the main chain oxygen of Cys106.

The calcium ion is coordinated by three main chain oxygen atoms from residues (Y 28, (G 30, (G 32, and two carboxylate oxygen atoms of (D 49.

The R1 amide group interacts with the side chain nitrogens of Gln120 and Asn152 and the main chain oxygen of Ser315.

The main chain oxygen atom of T417, and side-chain oxygens of N396, E445 and E450 are in a position to coordinate a calcium ion.

The phenyl ring of the bound inhibitor forms numerous van der Waals contacts in the S1 pocket of the enzyme, with the p-hydroxyl group donating a hydrogen bond to the main-chain oxygen atom of Ser217, and the o-hydroxyl group forming a water-mediated hydrogen bond with the carbonyl oxygen of Val227.

The ribose moiety mostly points towards solvent, although the 2'-hydroxyl is hydrogen bonded to the main-chain oxygen atom of Lys116.

It is also possible that Y2483 could donate a hydrogen-bond to the main-chain oxygen of T733 in FilGAP, thus, stabilizing FilGAP binding further.

The Ca2+ coordination assumed an octahedral geometry, as opposed to a more typical pentagonal bipyramid [32], using two side-chain oxygen molecules, two main-chain oxygen molecules (Asp1139, Val1156, Ile1208, and Asn1210), and two water molecules (Fig. 4A, right).

However, Ala62 completely lost the interaction with TP5 by its side chain oxygen which was replaced by the main-chain oxygen of Ala62 (Fig. 7C, D), suggesting that the interaction by the main chain weakened the binding affinity.