Sentence examples for main chain interactions from inspiring English sources

Thr-250 binds γ-phosphate through main chain interactions and Thr-251 (corresponding to Thr-35 in Ras) coordinates the γ-phosphate and also the Mg2+.

Briefly, main chain interactions between the backbone carbonyl and amide groups of Leu17 and Leu20, respectively, allow hydrogen-bond formation with the C2 amine of residue G0.

The K-loop also harbors a conserved motif 249GTTRD253 in switch-I region (Thr-251 corresponds to Thr-35 in Ras that coordinates both Mg2+ and γ-phosphate) and coordinates the K+ ion through main chain interactions via Thr-245 and Ile-247 [23].

While it seems that active site dimension contributes to potassium specificity, inspection of the active site of YqeH model suggests that like in MnmE, potassium is bound at the active site by main chain interactions with a part of switch-I, termed the K-loop, α and β phosphates of GDP, a fluoride ion (i.e. the γ-phosphate mimic) and the side chain of Asn-169 from P-loop (Fig. 4a).

Additional hydrogen bonds stabilize the peptide-motor complex through main chain interactions.

Consequently, tight binding of Tah1 to Hsp90 is determined within the conserved MEEVD motif, and upstream amino acids appear to be involved in mainly main chain interactions.

PSDT-C12 has a longer main chain (larger molecule weight) than PSDT-EH, which can favour a more extended main chain interaction.

The vibronic peak at 519 nm and shoulder at 563 nm in the PSDT-C12 film further confirmed stronger main chain interaction.

However, the peptide main chain interaction with the SH3 domains is conserved.

Specificity differences can be explained by differences in PDZ residues that are in contact with the peptide ligands, but these contacts involve both side-chain and main-chain interactions.

Human monoclonal antibodies 447-52D and 537-10D, both coded by the VH3 gene and specific for the third variable region (V3) of the HIV-1 gp120, were found to share antigen-binding structural elements including an elongated CDR H3 forming main-chain interactions with the N terminus of the V3 crown.