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The design rationale of reduction-sensitive polymers and conjugates usually involves incorporation of disulfide linkage(s) in the main chain, at the side chain, or in the cross-linker.
A similar degree of expansion of the polymeric main chain at the saturated binding concentration of various monovalent salts (LiCl, NaCl, KCl) was observed from measurement of intrinsic viscosity.
13C NMR spectrum (saturated solution, d-DMSO 40°C) of hemicellulosic substrate, RK72h, showed intense signals due to xylan main chain at 101.7, 75.3, 73.9, 72.5, 63.2 ppm, typical values of C1 (101.7) and C4 (75.3) linked β-xyloses.
The ED pattern of the protein structure shows that side chains extend from the main chain at regular intervals and these serve as definite diffraction units in determining the perpendicular distance, in the same plane, between the polypeptide chains.
The observation that an L290P mutant displayed a high level of activity independent of Ca(2+)/CaM or phosphorylation of T286 indicates that a change in the conformation of the polypeptide main chain at L290 might contribute to the mechanism for generating autophosphorylation-dependent autonomous activity.
This was due to a favorable change in binding enthalpy contribution suggesting that the main chain at position −5 participates in stabilizing molecular interactions.
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In all three complexes in the a.u., P249 and N250 at the beginning of the TRM make multiple contacts with the main chain atoms at the C-terminal end of Tat helix 35 44.
According to 13C NMR spectra, polar units were located both on the main chain and at the chain end.
This AGP (310 × 103 g/mol), which is water-soluble, contains β-1,3-linked galactopyranosyl main chain substituted at O-6 position with side chains containing galactose and arabinose residues.
Very recently, photosensitive o-nitrobenzyl methyl ester and disulfide bonds have been introduced into the main chain or at the block-junctions in conventional triblock copolymers to introduce the dual responsiveness to the non-cross-linkable micelles.
These authors showed by NMR experiments and methylation analysis that the α-glucan was composed of a (1→4 -linked main chain, substituted at O-6 by single units of α-glucose in the proportion 1→4 -linked
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