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Vascular smooth muscle cells (VSMCs) are the main cellular component in the arterial wall, and abnormal proliferation of VSMCs plays a central role in the pathogenesis of atherosclerosis and restenosis after angioplasty, and possibly in the development of hypertension.
ECs therefore constitute their main cellular component, but epithelial cells and other stromal cells (e.g. unclassified macrophages) are also present.
Chondrocytes are the main cellular component of articular cartilage.
The main cellular component of tumor stroma is represented by an activated form of fibroblasts called Cancer-Associated Fibroblasts (CAFs).
Additionally, in tumor cells, the main cellular component of HCC tissues, STAT3 activation could be regulated independently of Cirp expression.
Lymphocytes are the main cellular component of the adaptive immune system, which counteract infections and participate in tumor surveillance.
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At the end of spermatogenesis, the main cellular components coil within the sperm cell (Fig. 4C), a process that occurs in all other spiders studied (see [35]).
The JAK/STAT pathway, originally identified through its role in embryonic segmentation, has three main cellular components in Drosophila: the receptor Domeless, the Janus Kinase (JAK) Hopscotch, and the STAT transcriptional factor [106]–[108].
VSMCs are the main cellular components of neointimal lesions after vascular injury.
The main cellular components of the innate immune system within the liver are the Kupffer cells.
The main cellular components were 'cell' and 'cell junction', such as GO 0043232 and GO 0070013.
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