Sentence examples for main cell targets from inspiring English sources

In oligodendrocytes, a decreased presentation mediated by the LMP2 60HH variant of MBP epitopes (e.g. MBP111 119) on HLA-A*02 MHC could attenuate the cytotoxic activity of MBP-reactive CD8+ T cells against their main cell targets.

The main cell targets for HIV are mononuclear leukocytes bearing CD4 and the chemokine receptors CCR5 and CXCR4 [ 9- 13].

The main cells targeted by NTHi appear to be macrophages and epithelial cells.

The results of the recent study showed that, although CD5+ IgM+ B cells were the main cell type targeted in BLV-infected but clinically normal cattle, CD5- IgM+ B cells, CD4+ cells, and CD8+ T cells were infected to a greater extent than previously thought.

In this scenario, our aim was to investigate whether PRP freezing/thawing affected the release of GFs from platelets α-granules at two key experimental points: 1 hour (immediate release) and 7 days, as scheduled delivery time in the clinical application, by evaluating the effects on chondrocyte and synoviocyte cultures, the main cell populations targeted in the joint.

The main TSLP responsive B cell target seems to be a late pro B cell (B220+CD43+BP1+CD24+) [66], which in response to TSLP shows increased cell cycle progression [33].

Proximal tubular cells were the main target cells of LPA stimulation and Rho kinase signaling was activated in these cells.

Alveolar epithelial cells are the main target cells in the epithelial respiratory compartment exposed to noxious substances such as E. coli or acid [ 45].

Glandular epithelial cells are the main target cells of autoimmunity in pSS [ 33], currently considered to be an autoimmune epithelitis [ 34].

The main target cell of H5N1 avian influenza viruses (AIVs) in humans is type II alveolar epithelial cells [3], which express the α2,3-linked sialic acid abundantly [4].

In the case of Human Immunodeficiency Virus (HIV), quiescent T lymphocytes, besides macrophages the main target cell population in the human body, are readily infected by the virus, however do not support efficient replication due to multiple early post entry replication blocks [1].