Sentence examples for main cell fate from inspiring English sources

Our findings suggest the existence of two main cell fate determination centres within the pilosebaceous unit of mammalian skin.

We have presented here a network model that broadly covers the biology within five distinct yet overlapping cellular processes: DNA damage and the main cell fates resulting from cellular stress.

Due to cellular growth and proliferation, stem cells from the central zone move into the surrounding tissue where the spatial location of each daughter cell is a main determinant of cell fate.

Although the 4xGTIIC:FP transgene reports both Yap and Taz activity, Yap appears to be the main regulator of RPE cell fate.

This is highly significant because HES1, one of the main NOTCH target genes, controls cell fate decisions of the mammalian neural progenitor cells from which MBs arise (Solecki et al, 2001; Pomeroy et al, 2002).

Death receptors have a key role in mediating external signals to caspase8 in extrinsic pathway, and the mitochondria has a main role in deciding a cell fate in intrinsic pathway.

AP2 and RAV genes are the main actors in the determination of cell fate and development from meristems to fully developed organs.

TnrA regulates KipR, also detected in this module, whose main function is displayed during the sporulation cell fate [ 16] (more details are provided in the Additional file 1).

Until now, two main proposes are epigenetic and genetic modifications of cell fate.

The fluctuations of gene expressions due to intrinsic and extrinsic noise are essential for the cell fate differentiation at bifurcation points (see main text).

5 6 Cell fate seems to be directly controlled by two main Notch target genes: Hes1, a positive target, which stimulates the differentiation of progenitors into absorptive enterocytes; and Atoh1, a negative target gene that commits the progenitor to a secretory cell fate.