Eventually, even HLA as the primary cause of rejection has been questioned on the basis of rodent experiments [ 6].
Moreover, the bacterial colonization of bone substitutes is the main cause of implant rejection.
Microvascular thrombosis and fibrinolytic disorders have been recognized as main cause of allograft rejection in renal transplanted patients, but the pathway through which it occurs has not been clarified yet [ 10– 13].
Precision is one of the most important issues in the machining process, and the main cause for rejection is the part static deformation and the dynamic vibrations.
The color rejection threshold is considered to be the main cause of blooming artifacts, but adjustment of the color rejection settings alone does not eliminate the artifact completely 26, 29.
However, organ rejection is a thorny problem after transplantation, especially acute rejection which is the main cause of early dysfunction and retransplantation [ 21].
The main cause of the strike was the workers' overwhelming rejection of management's proposal to reduce wages for most workers unless they significantly sped up production.
Cardiovascular events, malignancy, infection, and chronic rejection are the main cause of mortality or allograft failure in KT patients, and the patients also suffer from metabolic and psychosocial complications and mineral bone disorder.
But the transplantation rejective response is a formidable problem after liver transplantation, especially acute rejection which is the main cause of early dysfunction and transplantation failure [ 7].
Because calcineurin inhibitors are used as immunosuppressive agents to avoid organ rejection, infections have emerged in the last 20 years as the main cause of death in the first year after transplantation [ 1, 2].
