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The Gram-positive bacterium S. pneumoniae is the main causative pathogen in community-acquired pneumonia (CAP), responsible for an estimated ten million deaths annually worldwide [1], [2], [3].
S pneumoniae was the main causative pathogen in CAP.
Clostridium difficile is the main causative pathogen of antibiotic-associated colitis.
Interestingly, susceptibility of the main causative pathogen Candida albicans to fluconazole remains stable [ 3, 4].
The main causative pathogen was methicillin-resistant S. α-haemolyticus (59 patients with pneumonia [72%]; 34 patients with bacteriaemias [79%]).
Human enterovirus 71 (EV71) is the main causative pathogen of hand, foot, and mouth disease (HFMD) in children.
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Main causative pathogens are equally represented by streptococci and staphylococci.
Main causative pathogens of BM have each one a peculiar seasonal pattern according to regions of the world.
Seasonal increases of BM observed in our study might be related with seasonal distribution of the main causative pathogens.
The main causative pathogens in CAP are Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis, which together account for approximately 85% of cases [ 12].
Streptococcus pneumoniae continues to be one of the main causative pathogens in community-acquired pneumonia and meningitis. 1 2 Owing to the high mortality of S pneumoniae infections, especially in older and very young patients, prophylactic use of 23-valent pneumococcal polysaccharide vaccine (PPV23) is recommended for people at an increased risk of pneumococcal disease in developed countries.
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