The main bottleneck that has prevented accurate electronic structure calculations from being applied to large molecules is the prohibitive scaling of computational cost with the number of electrons, say N, in a molecule.
The port city of Calais is the main destination for those trying to make the crossing, and the influx and resulting bottleneck has led to congestion and delays on both sides of the Channel, as well as reported millions of dollars worth of losses in revenue for the haulage industry.
However, the bottleneck has shifted.
That is where the bottleneck has occurred.
Forsey said "the potential bottleneck has been addressed".
One bottleneck has recently been converted from open prairie to an intensively developed natural gas field.
In our population, however, a bottleneck has not been evident.
The bottleneck has traditionally been the sequencing of binding clones.
Array printing could be the main bottleneck, as we have used a robotic work station to accurately spot each cDNA probe.
Because of the complex interactions and the many degrees of freedom, the calibration task itself has become a main bottleneck.
