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Our findings show that long homotypic K11-polyUb chains must adopt a conformation distinct from both K48 and K63 chains, as these both bind the proteasome in vitro, and suggest that the main binding surface for Ub 19S receptors, the I44 region, is not exposed in K11-polyUb conjugates.
In particular, the hydrophobic isoleucine (I44) region, which forms the main binding surface of Ub, is exposed in one model and buried in the other.
Similar(58)
The conformation of the central β-rich region may play an important role in RNA binding by modulating the interaction and presumptive binding surface between the two main domains, which could convey evolutionary advantages and virus specificity.
Ranchers can negotiate binding surface agreements to cover such damage, but to do so they need legal help.
In the 19th century Portland cement, a fine artificial powder, was the main binding agent in concrete.
The authors conclude a subsite binding of the second peptide unit close to the main binding pocket.
Soil organic carbon (SOC) and sesquioxides are main binding agents of aggregation while puddling is a disruptive force of aggregates.
Both observations suggest hydrophobic hydration involved in ice binding surface.
These results suggest that the Met4-Cbf1 binding surface is distinct from the Met4-Met31 surfand, and that the Met4-TFIID binding surface is closer to the Met4-Met31 surface, placing the Met4-TFIID binding surface near the 3' edge of the complex.
This surface overlaps highly with the Cdc42 binding surface (figure 6) [7].
IGFBP-3 is the main binding protein of IGF-I, and it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors (Hansel et al, 2004; Renehan et al, 2004).
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com