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In the main analyses a two stage approach will be taken.
In order to better visualize certain key effects from these main analyses, a supplementary subgroup classification was conducted on the older participants.
For the main analyses, a patient was considered to be a bisphosphonate user if they had at least one prescription during the observation period.
In the main analyses, a child was defined as impaired if the teacher reported "certainly true" on at least one of the two items.
Following the AHRQ model [ 22], we carried out two types of main analyses: a first one wherein transferred-out cases were excluded and a second one with exclusion of all transferred cases.
To put these results in context with common risk factors for atherosclerosis, in the same study population included in main analyses, a 10-year difference in age, adjusted by confounders in model 2, was associated with an 8%9595% CI: 7.3, 9.0) difference in IMTcca and an RRR of 10.3 (95% CI: 10.0, 10.5) for high versus normal ABI.
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In the crude main analyses, an increased odds for dementia among HUNT1-participants reporting mental distress (ADI-4 ≥ 88th percentile) compared to the remainder was identified (crude OR 1.52; 95% CI 1.15, 2.01; see Table 2).
For the main analyses, any mention of a condition on the death certificate was counted but a subgroup analysis restricted cases to those where the condition was the underlying cause of death.
Following H-C&C, we conducted two main analyses: (1) a cohort analysis and (2) a case-control analysis nested within the full cohort.
10 11 13 Lastly, we repeated our main analyses using a high dimensional propensity score that uses an algorithm to empirically identify candidate covariates.
This could be done by repeating the main analyses at a higher cut-off.
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