Sentence examples for main alterations are from inspiring English sources

The main alterations are discussed here.

It is noteworthy that all of the BRCA1 main alterations are mapped on exon 11.

Three main alterations have been described in CD patients.

The main molecular alterations are represented by variations in gene expression, usually mild and with consequences for a vast number of target protein coding genes.

Main ultra-structural alterations are revealed in the cell apical part.

Two main structural alterations were found to broaden the spectrum of biological activity in most cases.

The main histological alterations were epithelial hyperplasia (73.33%), basement membrane thickening (86.66%), edema, and fibrosis (93.33%).

The main histological alterations were edema (100%), inflammation (81.48%), basal membrane (bm) thickening (77.77%), and vessel proliferation (75.92%).

Interestingly, this shows a correlation between antifungal susceptibility and the amount of differentially expressed genes, which is a trend opposite to what would be expected if genetic alterations are the main reason for antifungal resistance in biofilms.

Therefore, although some genomic losses (for example, chromosome 1 in MDAMB361) or breakpoints (for example, chromosome 14 in MCF7) may contribute to PN miRNA downregulation and specific micro-deletions spanning PN miRNAs cannot at present be eliminated, it seems unlikely that genomic copy number alterations are the main mechanism underlying changes in their expression.

The main epigenetic mechanisms responsible for these alterations are represented by DNA methylation, posttranslational histone modifications, and regulation by noncoding microRNAs [ 4].