Similarly, progressing through Ar8, Ar4, Ar6, Ar10, Ar3, Ar2, Ar1, Ar7 and Ar5 the main affinities with the model legumes roughly follow through the spectrum with the last, Ar5, having predominantly violet (Lj2, Mt5) affinities.
The Arachis genetic map was substantially aligned with Lotus and Medicago with most synteny blocks presenting a single main affinity to each genome.
Although there are some regions of double affinities between Arachis and the model legumes, most synteny blocks have a single main affinity and not two affinities interleaved (Figs. 2, and 3).
The techniques are grouped according to the basic principles that govern cell separation, related to the main physical, affinity and biophysical characteristics of cells.
Although binding site II is thought to be the main high affinity binding site of leptin for leptin receptor [22], [25], [26], binding site III of leptin has been suggested to be responsible for formation of an active multimeric complex and subsequent activation of leptin receptor [5], [27].
CAR detected on human erythrocytes is the full-length molecule previously characterized as the main high affinity receptor for Ad5 and group B Coxsackie virus.
The main high-affinity root Fe uptake transporter IRT1 can also transport Zn (Rogers et al, 2000), and exposure to excess Zn can cause Fe deficiency symptoms (Fukao et al, 2011; Haydon et al, 2012).
Because the main high affinity targets of Tam are ERs and AEBS [ 5, 6, 8, 19, 20] and because of the synergistic effects between R115,777 and the ER ligand, results in agreement with data from Ellis et al. [ 21], together with the additive or synergistic effects observed with Tam, we had expected a negative effect with the combination that includes the selective AEBS ligand.
Possibly, this site, referred to as Box6, is an auxiliary operator site that supports binding to the main high-affinity operator sites, besides the intragenic Box4 and Box5, which were identified previously as secondary operator sites (Additional file 9: Figure S6) [ 35].
Additional file 3: List of the main known high affinity targets for sunitinib.
Aside from these major groups, there are also a number of fossil forms, mostly from the Early Cambrian, which are difficult to place, either from lack of obvious affinity to any of the main groups or from clear affinity to several of them.
