Sentence examples for main active form from inspiring English sources

As the main active form of intracellular thiamine (vitamin B1), thiamine pyrophosphate (TPP) is an essential cofactor in oxidative metabolism of the sugars, fatty acids and amino acids.

PDC2 encodes a transcription factor (Hohmann 1993) that regulates the availability of the pyruvate decarboxylase (PDC) isozymes Pdc1p and Pdc5p, which catalyze the reaction of pyruvate to acetaldehyde in the ethanol biosynthetic pathway [the main active form during glucose catabolism is PDC1 and PDC5 is a secondary form which is only expressed under thiamine starvation (Mojzita and Hohmann 2006)].

The main active form of PPARγ is the retinoid X receptor (RXR)/PPARγ heterodimer.

Ecdysteroids are a family of arthropod specific steroid hormones with 20-hydroxyecdysone (20E) as the main active form.

After absorption, thiamine is converted to thiamine pyrophosphate, which is the main active form of thiamine in vivo and functions as a coenzyme for the α-ketoglutarate dehydrogenase complex (α-KGDH), pyruvate dehydrogenase (PDH), and transketolase (TK) [ 14]. α-KGDH and PDH are two key mitochondrial enzymes involved in glucose metabolism and ATP generation by the Krebs cycle [ 15].

Modelling helps us to understand how the 20S proteasome catalyzes the degradation of specific proteins in cells (Pickering and Davies, 2012; Ben-Nissan and Sharon, 2014; Höhn and Grune, 2014; Fabre et al., 2015); it also forms the basis for future studies of the main active forms of proteasome in cells, for example, when it is bound to the regulatory complexes 19S and PA28 (Fabre et al., 2015).

The first hydroxylation converts vitamin D to 25-hydroxyvitamin D [25(OH D, which provides an indicator for nutritional vitamin D status] [2] and the second to the main active hormonal form, 1,25-dihydroxyvitamin D [1,25(OH)2D].

Furthermore, as the main transcriptional active form of PPARγ is in association with RXR (an orphan nuclear receptor, which binds to other environmental disruptors), additive (acting only through PPARγ) or synergistic (acting through both RXR and PPARγ) effects could occur, increasing the risk of metabolic diseases.

The two main biologically active forms of vitamin B12 (adenosylcobalamin and methylcobalamin) act as coenzymes and cofactors in complex rearrangement and methylation reactions, respectively [1].

These species form the main active sites for activating methane molecule.

XPS analysis showed that highly dispersed Mn oxides could form main active sites for Al-SBA-16-MA15 Al-SBA-16-MA15 Al-SBA-16-MA15 Al-SBA-16-MA15