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Exact(17)
We previously demonstrated that Peganum harmala extract and its main active constituents, harmine and harmaline decreased the TCDD-mediated induction of Cyp1a1 activity in mouse hepatoma Hepa-1c1c7 cells [ 8].
Furthermore, effect of this medicine was related with the main active constituents, along with the origin and the harvesting time.
The main active constituents in Calendula are terpenoids, flavonoids, coumarines, quinones and volatile oils [42].
Anthraquinones, flavonoids and stilbene glycosides are considered to be the main active constituents in PMC [6, 7].
Among them, gentiopicroside (3), one of the main active constituents, was the maximum amount among all the components in both "Long-Dan" and "Qin-Jiao".
The possible reasons might be that different harvesting time of the 17 samples led to various contents of the main active constituents, giving rise to the different anti-E.
Similar(42)
An example of such statement is the antiseptic activity of the essential oil of Eucalyptus globulus, higher than the activity shown by its main active constituent isolated, cineol or eucalyptol [ 43].
They are well documented for their anti-diabetic, anti-cancer, and antimicrobial activities with berberine as the main active constituent.
Nigellone (dithymoquinone) is the main active constituent of volatile oil of black cumin (Nigella sativa) seeds.
Thymoquinone (TQ), the main active constituent of black seed essential oil, exhibits promising effects against inflammatory diseases and cancer.
Tetrandrine (Tet), the main active constituent of Stephania tetrandra root, has been demonstrated to alleviate adjuvant-induced arthritis in rats.
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