Sentence examples for main activator of from inspiring English sources

It is commonly accepted that the endoperoxide bridge of the artemisnins is vital for its antitumor activity, while ferrous iron (either in free ferrous form or in haem form) was thought to be the main activator of the antitumor activity of artemisnins [145].

This observation has not been specifically studied but TZDs block activation of NF-κB [34], a main activator of muscle wasting [88], in addition to their effects on stimulating PGC-1α and mitochondrial biogenesis [89].

For example, the transcript level of the main activator of the classical pathway of complement activation (C1S) is down-regulated one day after injury.

Specifically, B-Raf is thought to be the main activator of MEK under normal conditions; Raf-1 activates MEK in response to stimulus [ 38].

Fak activity in ILC cells strongly correlated with c-Src activity, suggesting that c-Src is a main activator of Fak in LBC.

We found that under conditions of ORAI1 overexpression in cortical neurons, STIM1 is the main activator of TG-induced SOCE, whereas STIM2 regulates basal luminal Ca2+ levels and activates the constitutive calcium entry with the additional involvement of STIM1.

Slimfast encodes a transporter for the intracellular uptake of circulating amino acids (AAs), which are the main activators of TOR kinase activity.

Through the deposition of C3b and C4b, after parasite incubation with normal human serum or serum depleted of complement factors, we showed that the lectin and alternative pathways are the main activators of the complement system by T. cruzi in non-immune serum.

The main activators of STAT molecules are cytokine receptor associated Janus kinases (Jaks).

Testosterone and particularly dihydrotestosterone (DHT) are the main activators of the androgen receptor [ 10].

Addition of IL-1b or tumor necrosis factor alpha did not upregulate IL-16 mRNA, indicating that the NF-κB and p38 pathways are not the main activators of the IL-16 gene.