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It is generally believed that FcγRIIB acts mainly as a co-receptor to regulate the activation of the main activating immune receptors like FcγRI and BCR, which show high affinity to their ligand at nanomole range (Batista and Neuberger, 2000; Lu et al., 2015).
Because ABF1 itself is down-regulated, the main activating influence comes from MSN4.
Currently, Ang1 remains the best characterized of the angiopoietins and is believed to be the main activating ligand for Tie2.
Various tumours overexpress some microRNAs (miRNAs) targeting 3′ untranslated region (3′-UTR) of main activating ligand genes such as MICA, MICB and ULBP1 to avoid immune recognition.
Because we previously identified the estrogen-related receptor (ERR γ) as the main activating factor for the strong induction of PDK4 by matrix detachment, we tested if induction of MnSOD was also dependent on ERR γ.
Mutation and overexpression are the main activating mechanisms for the ras family of genes in human cancer and the variable tandem repeat (VTR) located at the 3' end of H-ras has been associated with this risk.
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Its main activates include transfer, coordination and management of transportation of oil and oil products through pipelines within Russia and abroad, and preventive, diagnostic, and emergency rehabilitation work on oil and petroleum products.
Our observations show that in the RAW 264.7 cell line the main activated genes were the ones controlled by the STAT1-STAT1 homodIRF1 (IRF1 and SOCS1) and containing GAS elements in their promoter region.
These species form the main active sites for activating methane molecule.
The elements of model can be described as follows: A Learning Instance, the key element to be observed in a SLE system, is a unit of learning that has activated the main activities represented in learning, which are accessible through HLIs.
A component with cold standby redundancy is based on a nonactive spare module that waits to be activated when the (main) active module fails.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com