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Our observations show that in the RAW 264.7 cell line the main activated genes were the ones controlled by the STAT1-STAT1 homodIRF1 (IRF1 and SOCS1) and containing GAS elements in their promoter region.
For the main activated areas, 78 100% of the individual subjects showed activation in that same area.
Meanwhile trapping experiments indicated that the O2− and h+ are the main activated species.
The incidence of HCC shows clear geographical variation with higher annual incidence in Asia and Africa than in Western countries; we aimed to review the literature to find if there are different trends in the main activated molecular pathways.
One of the main activated clusters was the medial prefrontal cortex (MPFC) which, as demonstrated in earlier work, plays a critical role in cognitive control [ 34, 35].
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It is generally believed that FcγRIIB acts mainly as a co-receptor to regulate the activation of the main activating immune receptors like FcγRI and BCR, which show high affinity to their ligand at nanomole range (Batista and Neuberger, 2000; Lu et al., 2015).
Its main activates include transfer, coordination and management of transportation of oil and oil products through pipelines within Russia and abroad, and preventive, diagnostic, and emergency rehabilitation work on oil and petroleum products.
Because ABF1 itself is down-regulated, the main activating influence comes from MSN4.
Currently, Ang1 remains the best characterized of the angiopoietins and is believed to be the main activating ligand for Tie2.
Various tumours overexpress some microRNAs (miRNAs) targeting 3′ untranslated region (3′-UTR) of main activating ligand genes such as MICA, MICB and ULBP1 to avoid immune recognition.
Because we previously identified the estrogen-related receptor (ERR γ) as the main activating factor for the strong induction of PDK4 by matrix detachment, we tested if induction of MnSOD was also dependent on ERR γ.
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