Sentence examples for main Ub interactions from inspiring English sources

It is also clear that in the major phosphoUb species, the main Ub interactions sites, the Ile44 and the Ile36 patches, are structurally intact and extensively utilized in crystal lattice interfaces (Fig 3).

This suggests that the extended construct used in the assay forms additional Ub interactions involving Ser65 of donor or acceptor Ub that cannot be formed when Ser65 is phosphorylated.

It interacts with polyUb chains of ≥4 subunits through the Josephin domain, and Ub interaction motifs (UIMs) in the C-terminal region.

DES completed preliminary Ub interaction experiments with R0RBR by NMR and synthesized spin-labelled pUb proteins for pUb R0RBR interaction experiments.

Altogether, this showed that the coordination of the catalytic triad through Ub interaction is important for OTULIN activation.

A second but not mutually exclusive possibility is that tight binding of AO7T to UbcM2 may limit the inhibitory Ub interaction that restricts UbcM2 activity whereas weak BRCA1-BARD1 bisding is more permissive for Ub Lys48 inhibition.

UBD-Ub interactions are usually weak and generate a dynamic protein network that is rapidly assembled and disassembled, thus hindering their study.

Moreover, an SH3BP1 splice-variant BARGIN (BGIN), which possesses a C-terminus polyubiquitin (Ub) binding module, inactivates Rac1 in a poly-Ub-interaction dependent manner.

All main effects and trait × main effect interactions were included.

There are three main anchoring interactions.

Specifically, our experiments revealed three main interactions.