We first examined Ndk binding to Rab molecules.
We next examined whether bound Ndk expresses GAP activity towards Rab molecules.
In contrast, recombinant Ndk from M. smegmatis, a non-pathogenic mycobacteria, had little or no effect on Rab molecules.
The biological activity of a GEF is only fulfilled if it produces a sufficient number of active Rab molecules in a given time.
Endosomes and carrier vesicles, for instance, need to contain the appropriate membrane-organizing Rab molecules to generate domains able to tether to each other in order to promote fusion (for example, Zerial & McBride, 2001).
We, therefore, analysed the vps9a-2 mutant, defective in the main RAB-F guanine-nucleotide exchange factor (Goh et al, 2007) as well as plants expressing a rab-A2aN125I dominant-negative mutant version for KNOLLE and sterol accumulation.
Ross Rebagliati won the giant-slalom event at the 1998 Winter Olympics, in Nagano, Japan, with THC, pot's main psychoactive molecule, in his blood.
Angiotensin II is the main effector molecule of the RAS.
These molecules react with the main molecules into the solution in our case, hexane, hexadecane, cyclohexane, and benzene and the main molecules are associated or polymerized.
Integrins are the main adhesion molecules of leukocytes.
