Sentence examples for magp 1 from inspiring English sources

Various alternative non-DSL type ligands have been identified to activate NOTCH, such as the adhesion molecule F3/Contactin (Hu et al., 2003), EGF-repeat factor DNER (Eiraku et al., 2005), EGF-like domain 7 (Schmidt et al., 2009), and Microfibrillar associated glycoproteins (MAGP) 1 and 2 (Miyamoto et al., 2006).

Morpholino knockdown of MAGP-1 expression in zebrafish resulted in abnormal vessel wall architecture and altered vascular network formation.

MAGP-2 can also interact with αvβ3 integrins via a RGD sequence that is not found in MAGP-1.

The microfibril-associated glycoproteins MAGP-1 and MAGP-2 are extracellular matrix proteins that interact with fibrillin to influence microfibril function.

In the mouse, MAGP-1 deficiency had little effect on elastic fibers in blood vessels and lung but resulted in numerous unexpected phenotypes including bone abnormalities, hematopoietic changes, increased fat deposition, diabetes, impaired wound repair, and a bleeding diathesis.

Loss of MAGP-1 around the hair follicle/pore areas was also observed, suggesting a possible correlation between MAGP-1 loss and enlarged pores in aged skin.

Next, we observed the in vivo change of MAGP-1 in human skin.

Our findings demonstrate that a critical "pre-elasticity" component, MAGP-1, declines with aging and photoaging.

Primary goat antihuman MAGP-1 and antihuman fibrillin-1 (Santa Cruz Biotechnology, Inc).

After repetitive low-dose UV exposure, a significant reduction in the MAGP-1 level was observed.

As age progresses, a near complete loss of MAGP-1 immunoreactivity was observed.