The number of mannose residues is higher for taliglucerase alfa than for imiglucerase; no direct comparison is made with velaglucerase alfa, which contains longer-chain high-mannose-type glycans, compared with the core mannose structures found on imiglucerase.
Although it is made with a signal sequence, only a fraction is secreted, the rest being targeted to the endo-lysosome pathway [90] due to mannose-6-phosphate receptor recognition of its N-linked saccharides [91].
The hemicellulose in spruce is mainly made up of mannose units, which are readily fermented by baker's yeast.
A movement of this loop would imply the disruption of numerous hydrogen bonds, making mannose binding energetically unfavorable.
Based on previous in vivo observations, the removal of α1,2-linked mannoses by ManI was considered in the following order [40], [41]: ER resident ManI removes free α1,2-linked mannose attached to α1,3-linked mannose in the initial input substrate and then Golgi resident ManI removes each of two remaining free α1,2-linked mannoses successively, making 6-mannose and then 5-mannose glycans.
Eun-Ho Eun-Ho Song havetalso designed glycopolymers with mannose and glucose moieties.
This effect has been demonstrated by replacing glucose with mannose, which does not directly inhibit the cellulase system, but its affinity for water makes this unavailable for the enzymes and hence reduces their performance [ 10].
The biosensing surface-confined mannose could effectively mimic the presentation of cell surface mannose and was responsible for competing with mannose on cancer cells in incubation solution.
SLNas were surface engineered with mannose residues to recognize mannose receptors located on infected alveolar macrophages and facilitate cell internalization.
To assess the interaction of human proacrosin/acrosin with mannose residues coupled to a protein backbone.
