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Calculations were made using nQuery Advisor 6.01.
Sample size calculation was made using nQuery® Advisor 5.0 (Statistical Solutions, Saugus, MA, USA).
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A priori power analyses for each class of primary hypotheses have been calculated using nQuery [ 115] assuming a two-sided test.
We powered to detect a difference in maximum pain score between the placebo and alfentanil group, using nQuery Advisor 7.0 (Statistical Solutions Ltd., Cork, Ireland).
Power calculations to attain 90% power with a significance level of 0.05 were performed using nQuery Advisor version 7.0 software.
A power calculation was conducted using nQuery Advisor (Version 7.0).
A blocked random allocation sequence was generated using nQuery Advisor (Statistical Solutions, Cork, [Ireland]).
Based on the reported SA nasal carriage of 27 to 37.2% in the general population but with previous rate reported around 35% in the literature (15, 29), we determined that the required population size for an expected SA carriage proportion of 35%, a precision of 8%, and a type 1 risk of 5% was 150 subjects, calculated using Nquery Advisor 7.0 (Statistical Solutions, Saugus, MA, USA).
Using nQuery Advisor 5.0 (Statistical Solutions, Cork, Ireland), we calculated a sample size of n = 34, resulting in a total sample size of n = 41 with a drop-out rate of 20%.
generated a randomisation list using nQuery.
All calculations were completed using nQuery Advisor® (Statistical Solutions Ltd, Boston, MA).
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com