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For assay validation, a few modifications were made to the procedure and are reported wherever applicable.
Additional improvements could also be made to the procedure for sampling from the parameter space.
This assessment will determine if the changes made to the procedure produced an equivalent formulation.
An overview of the changes made to the procedure is given in Table 1.
Here, modifications were made to the procedure used by Moon et al. to accommodate conjugation of the large molecular weight gp140 trimers.
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Small changes are made to the analysis procedure with respect to refs 18, 19 in order to achieve a consistent combination between the two experiments.
However, significant changes are made to the solution procedure, the most important of which is application of the arc-length method.
Further improvements were made to the test procedure by using post-ELISA virus release (VR), as an alternative to RNA extraction.
However, a slight modification was made to the synthetic procedure.
Following the withdrawal of the Super Aguri team's two entries, minor changes were made to the qualifying procedure.
Operational changes were subsequently made to the contact procedures.
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