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At the Enquirer, these offers for comment on critical articles are routinely made to subjects and just as often declined.
A phone call was made to subjects for invitation and to explain the study.
Nearly all patients were enrolled after seeking medical attention and therefore no inference can be made to subjects with age related white matter changes who are free of symptoms.
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Second, the study used a convenience sample and no attempt was made to randomize subjects to participants or vice versa.
Telephone calls have been made to 4372 subjects.
No further attempt will be made to recruit subjects who remain unwilling to participate.
A medical examination was made to identify subjects in good health.
To maximize the response rate, telephone calls were made to all subjects before each of the follow-up mailings.
No attempt is made to blind subjects or give equivalent amounts of intervention to the two groups.
Efforts were made to match subjects across groups in terms of age (±10 years), weight (±10 kg), sex, and race.
Efforts were made to match subjects across groups in terms of age (±10 years), weight (±10 kg), and sex.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com