Sentence examples for made this molecule from inspiring English sources

The fact that transgelin 2 was overexpressed and detected at a high rate (69%) in HCC specimens has made this molecule a candidate HCC marker for diagnosis.

Although it was first described as a molecule overexpressed in breast tumors, the discovering of its role as an NF- κB (nuclear factor κ-light-chain-enhancer of activated B cells) coactivator, together with some additional cytoplasmatic functions nonrelated to its histone acetylase activity and the overexpression in a broad spectrum of tumors, made this molecule an oncogene.

The ability of quercetin to inhibit signal 1 and prevent ASC oligomerization, directly inhibiting NLRP3 inflammasome activation make this molecule a potential therapeutic agent in inflammasome-mediated disorders.

A dithioamide BHPTC displayed promising antiproliferative activity in several cancerous cell lines, making this molecule an interesting lead compound for the design of new iron-chelating anticancer drugs.

Moreover, engineering an extra Zn II -binding peptide to the N-terminus of human endostatin makes this molecule more stable and cooperative in the presence of Zn II -binding

These desirable biophysical properties for TB31F, combined with its retained nanomolar binding affinity and potent activity to inhibit parasite transmission, make this molecule an attractive biologic for malaria interventions.

Therefore, the overall results validated each method and make this molecule as a potent MMP-2 inhibitor that blocked the invasion and could bring apoptosis at later stages in K562 cells sparing the normal ones.

Plasmodium vivax Duffy binding protein region II (DBPII) is an essential ligand for reticulocyte invasion, thereby making this molecule an attractive vaccine candidate against asexual blood-stage P. vivax.

The pleiotropic effects of melatonin, combined with its anti-oxidant, NMDA-blocking and anti-inflammatory properties, probably make this molecule an ideal candidate for pre-clinical studies.

Interestingly, the capacity of CD22 to internalize specific monoclonal antibodies was shown to make this molecule an effective target for immunoconjugate therapy of B-cell malignancies [51] [53].

The initial bronchoconstrictor effect observed with AZD9164 makes this molecule unfit for its intended purpose.