Sentence examples for made this gene from inspiring English sources

The known anti-apoptotic role of BCL-XL isoform (Boise et al., 1993) made this gene the prime candidate as a driver mutation in the 20q11.21 region.

Normal bone loss following ovariectomy made this gene uninteresting as an osteoporosis drug target.

Probably the absence of a TM8 ortholog in Arabidopsis made this gene of poor interest for further characterization.

It is precisely the tendency of COI to discriminate clearly among the named species in many invertebrate taxa that has made this gene a common reference tool for DNA barcoding and molecular taxonomy [ 27, 28].

The expression profile of claudin-1 in non-malignant versus tumor-derived cells has made this gene an interesting candidate for involvement in tumorigenesis, namely by acting as a suppressor of mammary epithelial proliferation.

Moreover, suitable conditions for amplification of Aldolase A were very flexible, ranging from a MgCl2 concentration of 1 to 5 mM (Fig. 1), 27 to 32 cycles (Fig. 2), and an annealing temperature of 55 to 65°C, which made this gene the ideal control, easily adaptable to combination with most other primer sets.

More recently, mutations in ARID2 were identified in NSCLC (7.3%), making this gene one of the most frequently mutated in this type of cancer (Manceau et al., 2013).

Moreover, labelled MSCs stably express the hPAP gene, thus allowing cell detection by classical histochemical methods, making this gene a useful tracking tool for further in vivo MRI validation.

Although it is also possible that the PLCB1 gene itself is regulated by PAX6 and CTCF, the fact that PLCB4 is directly related to circadian control makes this gene a more likely candidate.

All these features make this gene a promising candidate for BP regulation.

The specificity of the mutations makes this gene much more informative regarding clonal relatedness.