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This computational methodology has made substantial impact on many fields in science and also has profoundly changed engineering design procedures and practice.
However, despite four decades effort, none of them has yet made substantial impact because these IGCs are not sufficiently uniform and robust in meeting more rigid standards for electronic device applications.
While they have made substantial impact, current multicolor probes have many issues, including low detection specificity, low brightness, poor photostability, high manufacturing cost, low binding affinity, and low fluorescence enhancement upon activation.
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Just as philosophical ideas have fueled theological work, the great themes of theology involving God's transcendence, the divine attributes, providence, and so on, have made substantial impacts on important philosophical projects.
Syndromes were iteratively reviewed and refined until additional exclusion criteria were determined to no longer make substantial impact on the number of cases identified.
In terms of average closeness centrality, increasing or decreasing the percentage of insensitive nodes in network did not make substantial impact to the performance of our purposed technique.
The key reason that IBs have failed to make substantial impact is the lack of clear roadmap for IB validation and qualification.
Indels are frequent and can have substantial impact on function, which makes their detection all the more imperative.
Established by a generous donation from the Swiss entrepreneur and philanthropist Hansjörg Wyss, the Wyss Center presents a new model in translational neurotechnology research, offering competitively awarded support for projects that have the potential to make substantial clinical impact.
Cambodia has made substantial progress in preventing and mitigating the impact of HIV and AIDS, receiving a prestigious award at the Millennium Development Goal summit in September 2010.
"While past efforts to diversify our workforce have had significant impact on individuals," Collins said, "we have not made substantial progress in expanding diversity on a larger scale".
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