Sentence examples for made non-functional from inspiring English sources

It is likely that in this case MAP4K3 acts as part of a protein complex that can be made non-functional by changes in the stechiometry of its components.

Such a specific polymerase would have been much more efficient, as it would not waste its time making non-functional polymers.

You can't make it smaller without making it non-functional — so make it bigger.

Unfortunately, the operating voltage range of these devices barely exceeds 1 V, making them non-functional for many applications.

For instance, the sex-determining region (SRY gene) of the Y chromosome may be transferred to an X chromosome, resulting in an XX normal male, or it may undergo mutation making it non-functional, resulting in an XY female.

It plays a vital role either in destroying the suspicious object or making them non-functional by generating the gas pressure on burning of propellant against the water column inside the barrel.

A critical genetic defect in many tumors, including gliomas, is found in the p53 gene, which makes p53 non-functional.

Previously, we demonstrated that when RA signal cannot be integrated at RARα, because RARα is either not expressed, or has acquired genetic mutations that make it non-functional, the chromatin associated with RARβ2 falls into an aberrant exacerbated state of repression, which is unresponsive to RA [9].

Pseudo-gene has some deleterious mutations, which makes it non-functional.

Typically, these mutations are truncating and tend to destroy the protein product or make it non-functional.

There is a frame shift mutation in Rv2160A in M. tuberculosis that makes it non-functional in this species.