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Although the numerous potential fates of extracellular ATP [ 6] have made it difficult to pinpoint its precise role in the control of chemotaxis, inhibition of fMLP-mediated chemotaxis by addition of exogenous adenosine deaminase suggests that G-protein-coupled adenosine receptors are involved in the process [ 3].
But General Franks cautioned Friday that the Pentagon has received clashing information from surveillance aircraft, opposition sources and Americans forces that had made it difficult to pinpoint Mr. bin Laden's whereabouts.
Right then a man called to report an incident, insisting that he was northbound on I-287, a roadway that goes east-west, which made it difficult to pinpoint where he was.
A lack of data has traditionally made it difficult to pinpoint that potential but Google and Singaporean sovereign fund Temasek today released an update to their highly referenced 2015 'e-Conomy SEA' report — the main takeaway is that growth has exceeded their initial expectations.
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The derivatives market is known for its opacity, making it difficult to pinpoint an exact price in real time.
The interplay of biosocial factors inherently involved in epidemics make it difficult to pinpoint causality.
A start-up's initial sprint can be exciting, but it can also make it difficult to pinpoint when growth will start to decelerate.
Some symptoms can appear with other illnesses, and there is no test for the syndrome, which also makes it difficult to pinpoint.
The complexity and interconnectedness of each of the biogeochemical cycles make it difficult to pinpoint how any one human activity is altering the cycles; nevertheless, the majority of those who study these fluctuations agree that this is happening.
Migraine is a complex disorder that evolves due to a combination of multiple genes and external factors such as gene-environment, gene-nutrient, gene-gene interactions and epigenetics that result in multiple presentations of the disorder making it difficult to pinpoint the relevant genomic risk factors [6].
Extensive injury and surrounding hematoma may make it difficult to pinpoint the site of tunica disruption and associated US findings are used to support the diagnosis of testicular rupture; such supportive findings include a large testicular hematocele, contour abnormality of the testis, and heterogeneous echotexture of the testicular parenchyma (Fig. 2a).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com