This does not make essential oil.
Before publication, the authors need to make the following essential revisions: 1) The authors refer to the study of Georgescu et al. (EMBO, 2009) and suggest that the observed clamp-OB CTD interaction provides "an alternative explanation" for the reduced DNA synthesis seen by them.
Make "Essentials" one category.
Essential revisions: We were overall satisfied with the changes made in this paper since the last version that was reviewed.
[Editors' note: what now follows is the decision letter after the authors submitted for further consideration.] Essential revisions: We were overall satisfied with the changes made in this paper since the last version that was reviewed.
The paper makes an important contribution and should be published after certain revisions: Essential revisions: 1) Circuit diagrams: There's a logical problem in the circuit diagrams shown.
Essential revisions: 1) Using CskAS expressing OT1 T cells, the authors made the puzzling finding that the phosphorylation of the inhibitory tail pY505, the direct target of Csk, did not change in response to 3-IB-PP1 treatment.
Essential revisions are below.
Essential revisions: 1) The dose response analysis needs revision.
