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ERCP is often made difficult by duodenal motility.
Planning is made difficult by state budget uncertainties.
However, evaluations of their performance are made difficult by differences across patients and devices.
Its application is made difficult by the complex structure of these errors.
Their design is however made difficult by a lack of specifications, especially in European Standards.
This is made difficult by process nonlinearities, complex dynamics and tight manipulated variable saturation constraints.
The design task is particularly made difficult by the numerous different cases that need be analyzed.
Above all, private litigation was made difficult by the lack of an admission of guilt.
Access from the sea is made difficult by the surf and by a long submarine sandbar.
Rescue attempts were made difficult by the remote and treacherous location of the crash site.
"Our relationship is made difficult by the fact that we are in Italy.
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