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Our results indicate that genetically engineered hepatocytes and primary liver cells are more resistant than pancreatic β-cells to the adverse effects of cytokines offering hope that insulin secreting hepatocytesin vivo made by gene therapy are less likely to be destroyed by cytokines released during autoimmune destruction.
In most cases that have been investigated, the decision is made by gene regulation.
All observations made by gene array experiments were confirmed using real time PCR.
We defined the predictions made by gene expression within these pathways as the Patient-Specific Risk Profile (PSRP).
DNA encoding Ascl1b tagged with six copies of Myc at the C-terminus was made by gene synthesis (Genwiz).
Identification of mycobacterial species was made by gene probes (AccuProbe, Gen-Probe, San Diego, CA) for M. avium complex (MAC), M. gordonae and M. tuberculosis complex.
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Proteomics involves the large-scale study of the proteins that are made by genes.
Like all proteins, the 1,000 or so activators in the human body are themselves made by genes.
Since proteins are made by genes, one way to increase the amount of protein contained in the milk is to add an extra copy of the gene that serves as the recipe for that protein.
The largest part of vitamin D related genes in our list is made by genes differentially expressed in epithelial cells after treatment with the biological active form of vitamin D [ 56].
The contribution made by genes that are upregulated by B. cenocepacia upon treatment with polymyxin B to polymyxin B resistance must now be determined and is underway in the Valvano Laboratory.
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