Sentence examples for made assembly difficult from inspiring English sources

Of course, 100-year-old barn lumber is often less than perfectly square, so even though I cut the planks to the proper length, the varying width of each plank made assembly difficult.

While it features the same five-pad design as the Guitar Hero World Tour drum controller, many changes were made to address weight and size concerns that made assembly difficult.

These complications made assembly difficult for the second-generation sequencers.

However, any sequence variants among the reads, for instance due to genetic variation between individuals, sequencing of paralogs of a gene, or alternative splicing, can make assembly difficult.

Possibly some of these gaps are caused by simple sequence repeats (Chang et al. 2008) that make assembly difficult, and incorrect arrangement of some scaffolds using the linkage map may also have made it difficult to find BACs that bridge gaps.

Misassemblies are caused by the presence of repetitive DNA sequences that make assembly especially difficult because of the difference in the relative abundance of species present in the sample.

Unfortunately, reads sequenced from these types of samples often have a heterogeneous mix of various subpopulations with different variants, making assembly extremely difficult using existing assembly tools.

Genome sequencing of polyploid species has been avoided, because the homoeology of subgenomes made sequence assembly difficult.

These datasets comprise a smaller subset of sequence, with fewer repetitive elements, intron or intragenic sequences that make assembly of full genomes difficult.

The presence of small discrete elements, which must be accurately mounted and aligned, makes the assembly difficult and cumbersome.

A large number of repeats makes genome assembly difficult and cannot be resolved simply by increasing the sequencing depth e.g. using the next-generation low-cost sequencing platforms, due in large part to their short read lengths [ 36].