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To see if NF-AT3 could cause heart failure by itself, the researchers created mice that made an enzyme which kept the NF-AT3 pathway active, regardless of calcium levels.
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The section of DNA was found on chromosome three, next to a gene called TERC, which makes an enzyme that repairs telomeres when they shorten.
G6PD carries the instructions for making an enzyme that is essential for the transport of oxygen in the bloodstream.
They have found that bees cannot make an enzyme that other insects use to help eliminate toxins from the body.
The company, based in Dallas, said the patent covers the gene that makes an enzyme needed to produce paclitaxel, the active ingredient in Taxol, a cancer drug sold by Bristol-Myers Squibb, with $1.5 billion in annual sales.
Dr. Kari Stefansson, the chief executive of Decode, said that the new gene makes an enzyme that is a good target for drugs, and that the Roche pharmaceutical company in Switzerland was already testing several such drugs in laboratory rats.
The mutations spur cells to make an enzyme, telomerase, that keeps cells immortal by preventing them from gradually losing the ends of their chromosome, the telomeres.
They inserted the plasmids into cells infected with a virus that makes an enzyme for building RNA strands.
To make an enzyme industrially applicable, temperature is one of the most important parameters to determine the thermo-stability of the enzyme.
They also inserted a plant gene that makes an enzyme that converted these precursors into a compound resembling cholesterol, a progesterone precursor.
Cells in sperm, bone marrow, and other tissues that divide frequently make an enzyme called telomerase that prevents telomeres from shrinking.
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CEO of Professional Science Editing for Scientists @ prosciediting.com