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Through her and her husband Herb's extraordinary philanthropy, she made a vital difference to the issues that she cared about - and that matter to Americans.
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Having that personal power and visible local leadership can make a vital difference".
There are two simple things he must do, which will make a vital difference.
Having an early indication of a child's gestation can make a vital difference in these circumstances.
But having your desk and chair set up to suit you can make a vital difference to your health.
Each type of donor makes a vital difference for a small organization starting with little more than a wish and a promise.
Annual fund gifts to schools and programs across the University support the areas of greatest need, making a vital difference in the lives of students and faculty.
In such circumstances, an aide-memoire for stressed staff whose attention is being pulled in all directions could make a vital difference.
Cruz asserted that 54 million evangelicals did not vote in the 2012 election and that persuading 10 million of them to cast ballots in next year's general election could make a vital difference.
Decorative "feet" — three to a pot — are cheap and can make a vital difference in preventing waterlogged roots, especially if the pot sits directly on concrete or stone paving.
Tom Viita, senior UK political adviser at Christian Aid, said: "Aid is making a vital difference to millions of people around the world who are caught up in an unprecedented number of humanitarian crises.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com