Sentence examples for made a substantial effect from inspiring English sources

"His family made a substantial effect on our state, and you just can't take that away from him," said Al Heilman, 76, who said he still had a photograph socked away somewhere of himself meeting Mr. Romney's father decades ago.

What the stories above have in common is that while all of them made a substantial immediate impression, they will also likely have far-reaching effects that could be even more significant.

"Changing the name would have a substantial effect on our business".

The acidity range under which the two transporters are most active is different, indicating that minor changes in the amino acid sequence that make up their structure can have a substantial effect on the activity of these antiporters.

We made a substantial bid.

Last night, each made a substantial contribution.

In each case, it made a substantial profit.

Nothing seems to have made a substantial difference yet.

However, they made a substantial operating profit for some years.

AR made a substantial contribution.

All the authors made a substantial contribution.