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We made a substantial bid.
Last night, each made a substantial contribution.
In each case, it made a substantial profit.
BMK: made a substantial contribution to the research design and data acquisition.
Google made a substantial revision to its search algorithm today, the company says.
Nothing seems to have made a substantial difference yet.
However, they made a substantial operating profit for some years.
These contributions have made a substantial difference in the fight against HIV/AIDS.
You've made a substantial investment in establishing it in customers' minds and the broader marketplace.
The year she was 5, he made a substantial impression on Haley.
AR made a substantial contribution.
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