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In year 3 students attend laboratory courses in which microscopic and macroscopic specimens are viewed.
In a group consisting of up to 40 students separated into small groups, macroscopic specimens are circulated in defined intervals while students must solve problems related to their specimens in their group.
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The macroscopic specimen was solid and grayish with smooth margins (Fig. 2).
Macroscopic and microscopic specimens were evaluated by a pathologist in a blind fashion.
The macroscopic tumour specimens were gathered, frozen and cut into 1.7- to 2-mm thick slices.
The macroscopic tumour specimens were collected "en bloc", frozen and cut into 1.7- to 2-mm thick slices, then digitized for use as reference.
In Magdeburg, Germany the use of virtual techniques has even been expanded to macroscopic specimens which were digitalized and made available online to the students [ 19].
The macroscopic features of the specimens are shown in Table 1.
The defect sites were photographed and blindly scored by three different investigators by using the International Cartilage Repair Society ICRSscoringing system [ 20] (Table 1).> After macroscopic evaluation, the specimens were fixed in 10% formalin for 7 days and decalcified in 15% ethylenediaminetetraacetate (EDTA -buffered salinEDTA -bufferednsaline Nanjing, China) for approximately 14 daysolution
Although no macroscopic injuries to the specimens were detected on examination after loading, all specimens showed signs of microscopic injuries.
The macroscopic evaluation of the specimens is also important, because it can give additional information about their quality: colour, consistency and grade of immersion of the cylinders in formaldehyde can be useful criteria for knowing their suitability for diagnosis.
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